Check out the companies making the biggest moves midday:
Alkermes — The biotech company dropped 9% as traders weighed phase 2 trial results for its ALKS 2680 drug, which aims to treat narcolepsy. While the company will be advancing the drug to a Phase 3 trial, a higher range of doses or a split dosing regimen may be required to achieve effectiveness in some patients.
Bank stocks — The group rose broadly as Treasury yields declined, lifting the Dow Jones Industrial Average to all-time highs. Goldman Sachs and JPMorgan Chase rose 3.8% and 1%, respectively. The Financial Select Sector SPDR Fund (XLF) climbed 1%.
RXO — Shares popped 6%, adding to Tuesday’s 5.7%. The stock jumped in the previous session following a Morgan Stanley upgrade to overweight from equal weight. Wednesday’s move put the freight carrier on pace for its best day in more than a month.
Source: https://www.cnbc.com/2025/11/12/stocks-making-the-biggest-moves-midday-gs-amd-oklo-crcl.html